Disc-Flex
This comprehensive blend of nutrients, including vitamin D3 and K2, helps promote strength, flexibility, and comfort of spinal discs while maintaining a healthy calcium metabolism and Supports healthy immune mediator activity.
Suggested Use
As a dietary supplement, take 2 capsules daily, with meals, or as directed by a health professional.
Verifiable Science
This formula addresses the unique nutritional needs of intervertebral cartilage (IVC). IVC is avascular, wears differently, and is affected by different nutritional factors compared to articular cartilage. The basics of healthy disc composition involve glucosamine, chondroitin and collagen. Glucosamine supports spinal disc integrity and has the potential to support the strength of the disc under compressive loads.1In postmenopausal women, the healthy composition of the lumbar spine is directly related to collagen content.2 This formula may also support healthy advanced glycation end product activity, healthy immune mediator activity and healthy calcium metabolism. Advanced glycation end products may reduce the ability of the intervertebral disc to produce proteoglycans, which comprise healthy disc matrix.3 The age-related increase in advanced glycation end products also contributes to stiffening of the spine.4 l-Carnosine, grape seed extract and alpha lipoic acid help to maintain healthy advanced glycation end product metabolism and provide antioxidant protection.5 Cartilage end plate calcification also affects disc function and longevity. Vitamin K2as menaquinone-7 also maintains a healthy balance of calcium uptake into extra-skeletal tissues.6 Devil's claw supports day-to-day spinal comfort and flexibility as demonstrated by German studies,7 while boswellia offers key support for musculoskeletal comfort.8‡
References
Gruenwald J, et. al. Adv Ther. 2009 Sep;26(9):858-71.
Garnero P, et. al. Arthritis Rheum. 2004 Oct;50(10):3137-44.
Yokosuka K, et. al. J Neurosurg Spine. 2006 Oct;5(4):324-9.
Schauss AG, et. al. J Agric Food Chem. 2012 Apr 25;60(16):4096-101.
Dersoa G, et. al. Int J Mol Sci. 2016 Oct 28;17(11):1802.
Knapen MHJ, et. al. Osteoporos. Int. 2013 Sep;24(9):2499-507.
Chrubasik S, et. al. Phytomedicine. 1996 May;3(1):1-10.
Kimmatkar N, et. al. Phytomedicine. 2003 Jan;10(1):3-7.